Alpha-D-xyloside xylohydrolase

Alpha-D-xyloside xylohydrolase (EC 3.2.1.177, alpha-xylosidase) is an enzyme.[1][2][3][4][5][6][7] This enzyme catalyses the following chemical reaction

Hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.
Alpha-D-xyloside xylohydrolase
Identifiers
EC no.3.2.1.177
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme catalyses hydrolysis of a terminal, unsubstituted xyloside at the extreme reducing end of a xylogluco-oligosaccharide.

References

  1. Moracci M, Cobucci Ponzano B, Trincone A, Fusco S, De Rosa M, van Der Oost J, Sensen CW, Charlebois RL, Rossi M (July 2000). "Identification and molecular characterization of the first alpha -xylosidase from an archaeon". The Journal of Biological Chemistry. 275 (29): 22082–9. doi:10.1074/jbc.M910392199. PMID 10801892.
  2. Sampedro J, Sieiro C, Revilla G, González-Villa T, Zarra I (June 2001). "Cloning and expression pattern of a gene encoding an alpha-xylosidase active against xyloglucan oligosaccharides from Arabidopsis". Plant Physiology. 126 (2): 910–20. doi:10.1104/pp.126.2.910. PMC 111180. PMID 11402218.
  3. Crombie HJ, Chengappa S, Jarman C, Sidebottom C, Reid JS (January 2002). "Molecular characterisation of a xyloglucan oligosaccharide-acting alpha-D-xylosidase from nasturtium (Tropaeolum majus L.) cotyledons that resembles plant 'apoplastic' alpha-D-glucosidases". Planta. 214 (3): 406–13. doi:10.1007/s004250100631. PMID 11859845.
  4. Lovering AL, Lee SS, Kim YW, Withers SG, Strynadka NC (January 2005). "Mechanistic and structural analysis of a family 31 alpha-glycosidase and its glycosyl-enzyme intermediate". The Journal of Biological Chemistry. 280 (3): 2105–15. doi:10.1074/jbc.m410468200. PMID 15501829.
  5. Iglesias N, Abelenda JA, Rodiño M, Sampedro J, Revilla G, Zarra I (January 2006). "Apoplastic glycosidases active against xyloglucan oligosaccharides of Arabidopsis thaliana". Plant & Cell Physiology. 47 (1): 55–63. doi:10.1093/pcp/pci223. PMID 16267099.
  6. Okuyama M, Kaneko A, Mori H, Chiba S, Kimura A (May 2006). "Structural elements to convert Escherichia coli alpha-xylosidase (YicI) into alpha-glucosidase". FEBS Letters. 580 (11): 2707–11. doi:10.1016/j.febslet.2006.04.025. PMID 16631751.
  7. Larsbrink J, Izumi A, Ibatullin FM, Nakhai A, Gilbert HJ, Davies GJ, Brumer H (June 2011). "Structural and enzymatic characterization of a glycoside hydrolase family 31 α-xylosidase from Cellvibrio japonicus involved in xyloglucan saccharification" (PDF). The Biochemical Journal. 436 (3): 567–80. doi:10.1042/bj20110299. PMID 21426303.
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