Mannosylglycerate hydrolase
Mannosylglycerate hydrolase (EC 3.2.1.170, 2-O-(6-phospho-mannosyl)-D-glycerate hydrolase, alpha-mannosidase, mngB (gene)) is an enzyme with systematic name 2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate acylhydrolase.[1] This enzyme catalyses the following chemical reaction
- 2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate + H2O D-mannose 6-phosphate + D-glycerate
| Mannosylglycerate hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.2.1.170 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme participates in the mannosylglycerate degradation pathway of some bacteria.
References
- Sampaio MM, Chevance F, Dippel R, Eppler T, Schlegel A, Boos W, Lu YJ, Rock CO (February 2004). "Phosphotransferase-mediated transport of the osmolyte 2-O-alpha-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor". The Journal of Biological Chemistry. 279 (7): 5537–48. doi:10.1074/jbc.m310980200. PMID 14645248.
External links
- Mannosylglycerate+hydrolase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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