邪気

From Sinitic 邪氣／邪气 (xiéqì). The 氣／气 was simplified to 気 in Japan.

• On’yomi: Goon
• IPA^(key): [d͡ʑa̠ke̞]

邪(じゃ)気(け) • (jake) 

1. An evil or malevolent spirit.
2. An illness or disease.

• (malevolent spirit): 物(も)の怪(のけ) (mono no ke)
• (disease): 病気(びょうき) (byōki)

/dʑake/ → /dʑaki/

Shift in reading of 気 from go'on ke to kan'on ki.

• On’yomi
• (Tokyo) じゃ​き [jáꜜkì] (Atamadaka – [1])
• (Tokyo) じゃき [jàkí] (Heiban – [0])
• IPA^(key): [d͡ʑa̠kʲi]

邪(じゃ)気(き) • (jaki) 

1. A bad nature or disposition that could cause disease.
2. Malice, maliciousness, a menace, ill will.
3. An evil or malevolent spirit.
4. An evil aura or chi emitted from an evil spirit.
5. A cold, an illness.

• (bad nature): 悪気(わるぎ) (warugi)
• (malice): 悪意(あくい) (akui)
• (malevolent spirit): 物(も)の怪(のけ) (mono no ke)
• (a cold): 風邪(かぜ) (kaze)

/dʑake/ → /zake/

Shift in reading of 邪 from go'on ja to non-affricated za.

• On’yomi: Goon
• IPA^(key): [d͡za̠ke̞]

邪(ざ)気(け) • (zake) 

1. An evil or malevolent spirit.
2. A curse.

• (malevolent spirit): 物(も)の怪(のけ) (mono no ke)
• (curse): 祟(たた)り (tatari)