MPTP

English

Pronunciation
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Initialism

MPTP

  1. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Noun

MPTP (uncountable)

  1. (neurotoxicology) A byproduct of synthetic heroin, or MPPP, which causes Parkinsonian symptoms in users.
  2. (neurotoxicology) A neurotoxin which degrades into MPP+ after crossing the blood brain barrier, which causes a degredation of the dopaminergic neurons within the substantia nigra.

Quotations
  • 2005 Dec 29 Petzinger, et al. Journal of Neuroscience Research
    The neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine MPTP provides an excellent opportunity to study repair and response to injury in the basal ganglia.
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