goitrogen

English

Etymology

Coined some time between 1945 and 1950, from goitre +‎ -o- +‎ -gen.[1][2]

Pronunciation
  • IPA(key): /ˈɡɔɪtɹədʒən/, /-ˌdʒɛn/

Noun

goitrogen (plural goitrogens)

  1. Any agent that causes goiter, such as thiouracil.
    • "We have previously shown that treating rats with the reversible goitrogen 6-propyl-2-thiouracil (PTU) from birth to Day 25 increases testis size and sperm production in adulthood by up to 80% and 140%, respectively."[3]
    • "These results suggest that excess iodine induces thyroid involution in goitrogen-treated rats at least partially by apoptosis."[4]

Derived terms

References
  1. Goitrogen in Dictionary.com
  2. Goitrogen in Merriam-Webster
  3. P. S. Cooke, J. Porcelli, R. A. Hess. Induction of increased testis growth and sperm production in adult rats by neonatal administration of the goitrogen propylthiouracil (PTU): the critical period. Biology of Reproduction. January 1992;46(1):146-54.
  4. [R. B. Burikhanov and S. Matsuzaki. Excess iodine induces apoptosis in the thyroid of goitrogen-pretreated rats in vivo. Thyroid. February 2000;10(2):123-9.]
This article is issued from Wiktionary. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.