Aluminum hydroxide/magnesium hydroxide/simethicone

Aluminum hydroxide/magnesium hydroxide/simethicone
Combination of
Aluminum hydroxideAntacid
Magnesium hydroxideAntacid
SimethiconeAntiflatulent
Names
Trade namesAlmagel Plus,[1] Diovol Plus,[2] Maalox, Mylanta, others[3]
Clinical data
Main usesHeart burn, indigestion, abdominal bloating, discomfort from overeating[4][3]
Side effectsDiarrhea, constipation, low potassium[1][3]
InteractionsDigoxin, phenytoin, tetracyclines, quinolones[1]
BreastfeedingAl OH (safe)[5][6]
Mg OH (safe)[7]
Simethicone (safe)[8]
Legal
Legal status

Aluminum hydroxide/magnesium hydroxide/simethicone is a combination medicine used to help with heart burn, indigestion, abdominal bloating, and discomfort from overeating.[4][3] It is available as a liquid or pill, which is taken by mouth.[3]

Side effects may include diarrhea, constipation, or low potassium.[1][3] It may decrease the absorption of other medications.[3] Care should be taken in people with kidney problems.[1] Use is regarded as okay when breastfeeding.[9][10] The components aluminum hydroxide and magnesium hydroxide are antacids while simethicone decreases intestinal gas.[2] The benefit of having both aluminum and magnesium antacids is that there is generally little change in bowel movements.[11]

In the United States a 350 ml bottle costs about 10 USD as of 2023 and is available over the counter.[12] It is sold under more than 50 brand names including Diovol Plus and Maalox.[2][3] Different flavors are available.[3]

Medical uses

Dosage

The typical dose is 10 to 20 mL up to four times per day.[1]

Society and culture

Cost

The cost of this medication in the U.S. is $12 (USD) for 355 ml oral suspension 200 mg-200 mg-20 mg/5 mL.[12]

References

  1. 1 2 3 4 5 6 "CW Online Formulary". www.pedmed.org. Archived from the original on 4 July 2020. Retrieved 12 May 2023.
  2. 1 2 3 "Aluminum/Magnesium Antacid/Simethicone - Oral". myhealth.alberta.ca. Archived from the original on 29 January 2023. Retrieved 12 May 2023.
  3. 1 2 3 4 5 6 7 8 9 "Aluminum hydroxide, magnesium hydroxide, and simethicone Uses, Side Effects & Warnings". Drugs.com. Archived from the original on 28 January 2021. Retrieved 12 May 2023.
  4. 1 2 "DailyMed - MINTOX- aluminum hydroxide, magnesium hydroxide, simethicone suspension". dailymed.nlm.nih.gov. Retrieved 12 May 2023.
  5. ↑ "Aluminum hydroxide Use During Pregnancy". Drugs.com. Archived from the original on 21 October 2020. Retrieved 13 April 2021.
  6. ↑ "BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs". WHO.int. Archived from the original on 27 August 2021. Retrieved 14 April 2021.
  7. ↑ "Magnesium Hydroxide". Drugs and Lactation Database (LactMed). National Library of Medicine (US). 2006. Archived from the original on 5 March 2021. Retrieved 13 April 2021.
  8. ↑ "Aluminum hydroxide / magnesium hydroxide / simethicone Use During Pregnancy". Drugs.com. Archived from the original on 20 January 2021. Retrieved 13 April 2021.
  9. ↑ Mannel, Rebecca; Martens, Patricia J.; Walker, Marsha (18 June 2012). Core Curriculum for Lactation Consultant Practice. Jones & Bartlett Publishers. p. 443. ISBN 978-0-7637-9879-6.
  10. ↑ "Aluminum hydroxide / magnesium hydroxide / simethicone Use During Pregnancy". Drugs.com. Archived from the original on 20 January 2021. Retrieved 13 May 2023.
  11. ↑ Acosta, W. Renee (8 June 2020). Pharmacology for Health Professionals. Jones & Bartlett Learning. p. 269. ISBN 978-1-284-24083-2.
  12. 1 2 "Aluminum hydroxide/magnesium hydroxide/simethicone Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 10 April 2021. Retrieved 13 April 2023.
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