Antisialagogue

Antisialagogues are drugs or substances that decrease the flow rate of saliva and their effect is opposite to that of sialagogues.[1] Their origin may be both natural and synthetic.

Anticholinergics generally have antisialagogue effects, and most produce some level of sedation, both being advantageous in surgical procedures.[2]


Classic antisialagogues[1] include:

  • atropine,
  • opium,
  • alkalies,
  • belladonna,
  • hyoscyamus,
  • stramonium,
  • tobacco in excess,
  • all nauseous or insipid substances.

References

  1. 1 2 Dock LL (1916). "Drugs Acting On The Salivary Glands". Text-Book Of Materia Medica For Nurses. G. P. Putnam's Sons. Retrieved 15 October 2010.
  2. ↑ Hata TM, Moyers JR (2009). "Preoperative Patient Assessment and Management". In Cahalan MD, Barash PG, Cullen BF, Stoelting RK (eds.). Clinical Anesthesia. Hagerstwon, MD: Lippincott Williams & Wilkins. p. 592. ISBN 978-0-7817-8763-5.
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